Public Health and Toxicology Issues in Drug Research, Volume 2: Toxicity and Toxicodynamics

Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two explores the implications of pharmaceuticals, chemicals, food toxicants, dietary phytochemicals, and medical treatments on public health, with a focus on pharmacokinetics and toxicokinetics, bioaccumulation, and drug-induced toxicity. It also covers ethical, legal, societal, and professional issues in toxicology, making it a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of these substances.

Format: Paperback / softback
Length: 852 pages
Publication date: 28 March 2024
Publisher: Elsevier Science Publishing Co Inc

Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two is a comprehensive book that explores the implications of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on public health. It covers various topics such as pharmacokinetics and toxicokinetics, population pharmacokinetics/toxicokinetics, toxicokinetic studies, preclinical safety assessments, bioaccumulation of pharmaceutical and personal care products, drug-induced toxicity, and mechanistic pathways of food toxicants. Additionally, it discusses ethical, legal, societal, and professional issues in toxicology, making it a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

The book begins by discussing the pharmacokinetics and toxicokinetics of pharmaceuticals and chemical and food toxicants. It explains how these substances are absorbed, distributed, metabolized, and excreted in the body and how they can affect different systems of the body. The design of toxicokinetic studies is also discussed, including the use of toxicokinetic data in preclinical safety assessments.

One of the key topics covered in the book is the bioaccumulation of pharmaceutical and personal care products. It explains how these substances can accumulate in the body over time and how they can have negative health effects. The book discusses the health effects of bioaccumulation, including cancer, reproductive problems, and neurological disorders.

Drug-induced toxicity is another important topic covered in the book. It explains how drugs can cause adverse effects on the body and how these effects can vary depending on the dose, route of administration, and individual characteristics. The book discusses the mechanisms of drug-induced toxicity, including pharmacokinetics, pharmacodynamics, and toxicodynamics.

The book also investigates the health effects of dietary phytochemicals. It explains how these substances can have positive health effects, such as reducing the risk of cancer, heart disease, and diabetes. The book discusses the mechanisms of action of dietary phytochemicals, including antioxidant, anti-inflammatory, and anti-cancer properties.

Ethical, legal, societal, and professional issues in toxicology are also discussed in the book. It explains how these issues can impact the development and use of pharmaceuticals, dietary supplements, personal care products, and medical treatments. The book discusses the ethical considerations of drug testing, the legal requirements for drug approval, and the societal impact of drug-related harm.

In addition to the topics covered in the book, the book also includes several case studies and examples to illustrate the practical applications of toxicology. These case studies include the development of new drugs, the regulation of pharmaceuticals, and the impact of drug-related harm on individuals and communities.

Overall, Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two is a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments. The book covers a wide range of topics and provides a comprehensive overview of the field. It is well-written and easy to read, and it includes numerous illustrations and tables to help illustrate the key concepts.

In conclusion, Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two is a comprehensive book that explores the implications of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on public health. It covers various topics such as pharmacokinetics and toxicokinetics, population pharmacokinetics/toxicokinetics, toxicokinetic studies, preclinical safety assessments, bioaccumulation of pharmaceutical and personal care products, drug-induced toxicity, and mechanistic pathways of food toxicants. Additionally, it discusses ethical, legal, societal, and professional issues in toxicology, making it a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

Weight: 450g
Dimension: 234 x 191 (mm)
ISBN-13: 9780443158421