Scattering Methods in Structural Biology Part B

The book Scattering Methods in Structural Biology, Part B, Volume 676 in the Methods in Enzymology serial, highlights advances in the field, presenting chapters on Quality controls, Refining biomolecular structures and ensembles by SAXS-driven molecular dynamics simulations, Data analysis and modelling of small-angle scattering data with contrast variation, Observing protein degradation in solution by the PAN-20S proteasome complex: state-of-the-art and future perspectives of TR-SANS as a complementary tool to NMR, crystallography and Cryo-EM, Extracting structural insights from chemically-specific soft X-ray scattering, Reconstruction of 3D density of biological macromolecules from solution scattering, ATSAS- present state and new developments in computational methods, and much more.

Format: Hardback
Length: 460 pages
Publication date: 15 October 2022
Publisher: Elsevier Science & Technology

Scattering Methods in Structural Biology, Part B, Volume 676 in the Methods in Enzymology serial, presents a comprehensive overview of advancements in the field. The book comprises chapters that delve into various aspects of structural biology. These chapters cover topics such as Quality controls, Refining biomolecular structures and ensembles by SAXS-driven molecular dynamics simulations, Data analysis and modelling of small-angle scattering data with contrast variation, Observing protein degradation in solution by the PAN-20S proteasome complex: state-of-the-art and future perspectives of TR-SANS as a complementary tool to NMR, crystallography, and Cryo-EM, Extracting structural insights from chemically-specific soft X-ray scattering, Reconstruction of 3D density of biological macromolecules from solution scattering, ATSAS: present state and new developments in computational methods, and much more.

Additional chapters in the book explore Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles (FoXSDock and MultiFoXS), Validation of macromolecular flexibility in solution by SAXS, Combining NMR, SAXS, and SANS to characterize the structure and dynamics of protein complexes, Application of Molecular Simulation Methods to Analyze SAS Data, and other relevant topics.

This comprehensive volume serves as a valuable resource for researchers and students in structural biology, providing cutting-edge insights and techniques for studying biomolecular structures and dynamics. The authors, experts in their respective fields, have contributed their knowledge and expertise to ensure that the content is up-to-date and relevant to the current research landscape.

With its extensive coverage and detailed explanations, Scattering Methods in Structural Biology, Part B, Volume 676 is an essential tool for anyone seeking to advance their understanding of structural biology. Whether you are a novice or an experienced researcher, this book will provide you with the knowledge and tools necessary to tackle complex structural challenges and make significant contributions to the field.

Dimension: 229 x 152 (mm)
ISBN-13: 9780323991810