Single-Domain Antibodies: Methods and Protocols

This volume covers current and emerging techniques for studying single-domain antibodies (sdAbs) in camelids and sharks, isolation of sdAbs, protein engineering approaches to optimize the solubility, stability, valency, and antigen binding affinity of sdAbs, and specialized applications of sdAbs. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Format: Hardback
Length: 612 pages
Publication date: 15 February 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into the latest and emerging techniques for studying single-domain antibodies (sdAbs). It serves as a valuable guide for researchers seeking to understand the biology and immunology of sdAbs in camelids and sharks, as well as their isolation, protein engineering approaches to enhance solubility, stability, valency, and antigen binding affinity, and specialized applications. Written in the style of the highly successful Methods in Molecular Biology series, each chapter encompasses an introduction to the topic, a comprehensive list of necessary materials and reagents, insightful tips on troubleshooting and potential pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Single-Domain Antibodies: Methods and Protocols strives to be a indispensable resource for researchers seeking to advance their knowledge in this field. By providing a thorough exploration of sdAbs, this book aims to facilitate groundbreaking discoveries and advancements in various scientific disciplines.

Weight: 1362g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071620748
Edition number: 1st ed. 2022