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Targeted Metallo-Drugs: Design, Development, and Modes of Action
Targeted Metallo-Drugs: Design, Development, and Modes of Action
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Excellent- More about Targeted Metallo-Drugs: Design, Development, and Modes of Action
The 24th volume of the Metal Ions in Life Sciences (MILS) series, titled "Targeted Metallo-Drugs: Design, Development, and Modes of Action," focuses on inter-disciplinary research in Biological Inorganic Chemistry. The volume explores innovative metallo-drug candidates that enhance cancer cell selectivity, possess new modes of action, and target resistance pathways, with contributions from international experts. It covers various agents, including anticancer, antimicrobial, antiviral, and tropical diseases, and highlights recent developments targeting COVID-19. Advanced spectroscopic methods and metallomics are used to elucidate the modes of actions of metallo-drugs.
Format: Hardback
Length: 370 pages
Publication date: 15 May 2023
Publisher: Taylor & Francis Ltd
The 24th volume in the Metal Ions in Life Sciences (MILS) series, titled "Targeted Metallo-Drugs: Design, Development, and Modes of Action," serves as a vibrant platform for inter-disciplinary research in Biological Inorganic Chemistry. Fueled by the clinical success of cisplatin as a leading anticancer drug, scientists worldwide have embarked on a mission to identify new metallo-drugs with the potential to overcome the limitations associated with cisplatin, such as dose-limiting toxic side effects and acquired or intrinsic drug resistance. This pursuit has led to the development of innovative metallo-drug candidates that exhibit enhanced cancer cell selectivity, thereby reducing toxic side effects, and/or possess novel modes of action to improve efficacy and target resistance pathways.
MILS-24, comprising 12 comprehensive and well-illustrated chapters, encompasses over 1600 citations, 100 figures, and 10 tables, with key contributions from 32 international experts from Europe, Asia, and North and South America. Beyond keeping the scientific community abreast of the latest developments, this publication serves as an invaluable resource for stimulating further research in targeted metallo-drug design and development.
The scope of MILS-24 extends to various therapeutic agents, including anticancer, antimicrobial, antiviral, and agents targeting tropical diseases, cyanide poisoning, and radiometals in molecular imaging and therapy. It highlights recent advancements in metallo-drug developments specifically targeting COVID-19. Furthermore, it emphasizes the importance of advanced spectroscopic methods and metallomics as powerful tools for elucidating the modes of actions of metallo-drugs.
By fostering interdisciplinary collaboration and sharing knowledge, MILS-24 plays a pivotal role in advancing our understanding of metallo-drug mechanisms and their applications in medicine. This series continues to be a valuable resource for researchers, clinicians, and students alike, contributing to the progress of biological inorganic chemistry and its translation into clinical practice.
Dimension: 229 x 152 (mm)
ISBN-13: 9781032223308
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